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What Is Supartz?

What Is Supartz?

Your doctor has determined that the knee pain you are experiencing is caused by osteoarthritis and that you may be a candidate for non-surgical, drug-free, pain-relieving Supartz joint fluid therapy.

Supartz joint fluid therapy is used for the treatment of pain in osteoarthritis of the knee in patients who have failed to get adequate relief from simple painkillers or from exercise and physical therapy. Supartz joint fluid therapy is a solution consisting of highly purified sodium hyaluronate (hyaluronan). Hyaluronan is a natural substance found in the body and is a common constituent of connective tissues and the thick, viscous fluid (synovial fluid) found in joints. Hyaluronan acts like a lubricant and shock absorber in synovial fluid of a healthy joint. Osteoarthritis reduces your synovial fluid’s ability to protect and lubricate your joint.

Global Leader

Supartz joint fluid therapy is the most commonly used joint fluid therapy in the world. More than 119 million Supartz joint fluid therapy injections have been sold worldwide since its introduction in 1987. This wealth of clinical experience provides you with the confidence that Supartz joint fluid therapy, the world’s most prescribed joint fluid therapy is both safe and effective. It was also the first hyaluronan in the world available commercially for human use in treating the pain of osteoarthritis.


In the five clinical studies conducted, adverse events occurred at similar rates in the patients treated with Supartz joint fluid therapy as those treated with the saltwater placebo. The following were the most common adverse events: joint pain with no evidence of inflammation, joint pain with evidence of inflammation, back pain, pain (non-specific), injection site reaction, headache and injection site pain. No severe allergic reactions were observed in any study patients. Five (5) mild to moderate allergic reactions were reported in the Supartz joint fluid therapy group. No anaphylactic reactions were observed in any study patients.


The extensive worldwide clinical history of Supartz joint fluid therapy gives your doctor the confidence that Supartz joint fluid therapy will safely offer you relief from your knee pain.

Active Ingredient

Supartz joint fluid therapy administers more active ingredient per series directly to the site of your knee pain.

Supartz is a trademark of Seikagaku; Smith & Nephew; Bioventus.
 Contents Courtesy of Seikagaku; Smith & Nephew; Bioventus