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Risk Factors for Myelodysplastic Syndrome (MDS)
Exposure to Radiation
Exposure to Certain Drugs and Chemicals
- Petrochemicals—chemicals derived from petroleum or natural gas, such as ethyl alcohol
- Benzene—a distillation product from coal and petroleum that is used as a solvent and as a fuel
- Alkylating agents
Genetics and Birth Defects
- Down’s syndrome —This is a relatively common genetic disorder that results in birth defects, medical problems, and some degree of intellectual disability.
- Fanconi anemia—This condition is an inherited form of anemia that leads to bone marrow failure.
- von Recklinghausen’s disease (neurofibromatosis type 1)—This is a genetic disorder of the nervous system that causes tumors to grow on the nerves in any part of the body. The condition may also produce changes in the skin and bone deformities.
Castro-Malaspina H, O’Reilly RJ. Aplastic anemia and the myelodysplastic syndromes. In: Kasper DL, Harrison TR. Harrison's Principles of Internal Medicine. 14th ed. New York, NY: McGraw-Hill; 1998.
Silverman LR. Myelodysplastic syndrome. American Cancer Society website. Available at: http://www.nci.nih.gov/cancer%5Finformation/ . Accessed November 30, 2002.
- Reviewer: Mohei Abouzied, MD, FACP
- Review Date: 12/2013
- Update Date: 01/13/2014