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Could Your Depression Be Related to Your Medication?
Symptoms of Depression
- Persistent feelings of sadness, anxiety, or emptiness
- Restlessness or irritability (may be only symotoms present in children or adolescents)
- Feeling guilty, worthless, or helpless
- Loss of interest in hobbies and activities
- Feeling tired
- Trouble concentrating, remembering, making decisions
- Trouble sleeping, waking up too early, or oversleeping
- Changes in appetite or weight
- Thoughts of death or suicide, with or without suicide attempts
- Physical symptoms without a standard diagnosis and not responding well to medical treatment
Medications Reported to Cause Depression
- Triptans for migraine headaches
- Oral contraceptives or other hormonal treatments
- Medications to treat other psychiatric conditions
- Anti-seizure medications
- Oral acne medications (isotretinoin)
- Medications used to quit smoking
- Certain antiviral medications
- Cardiovascular medications
How Other Factors Come into Play
- Chronic illness, like cancer or heart disease
- Unknown or unrecognized mental illness
- Social factors, like unemployment or disability
- Past history with depression
Talk to Your Doctor
National Institute of Mental Health http://www.nimh.nih.gov
The National Mental Health Association http://www.nmha.org
Canadian Mental Health Association http://www.ontario.cmha.ca
Canadian Psychiatric Association http://www.cpa-apc.org
Botts S, Ryan M. Depression. Association Schools of Public Health website. http://www.ashp.org/DocLibrary/Policy/Suicidality/DID-Chapter18.aspx PDF. Accessed November 13, 2012.
Depression. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated October 2, 2014. Accessed October 16, 2014.
Drug safety information. US Food and Drug Administration website. Accessed at http://www.fda.gov/Drugs/ResourcesForYou/HealthProfessionals/DrugSafetyInformation/default.htm. Updated May 17, 2012. Accessed October 16, 2014.
Kotlyar M, Dysken M, Adson DE. Update on drug-induced depression in the elderly. Am J Geriatr Pharmacother. 2005;3:288-300.
Patten SB, Barbui C. Drug-induced depression: a systematic review to inform clinical practice. Psychother Psychosom. 2004;73:207-215.
- Reviewer: Michael Woods, MD
- Review Date: 10/2014
- Update Date: 10/16/2014