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Conditions InDepth: Scleroderma
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- Morphea—Skin lesions are firm, at times oval, whitish or brownish plaques, surrounded by a purplish ring.
- Linear—Skin lesions appear as hardened streaks or lines along the arms, legs, or forehead.
- Limited—A gradually progressing form of scleroderma that initially causes skin thickening, but progresses to affect the internal organs.
- Diffuse—A more quickly progressing form of scleroderma that causes the skin to thicken throughout the body. It may also affect the internal organs.
Systemic Sclerosis Sine Scleroderma
Iaccarino L, Gatto M, et al. Overlap connective tissue disease syndromes. Autoimmun Rev. 2013;12(3):363-373.
Systemic sclerosis. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed.ebscohost.com/about/about-us . Updated August 5, 2013. Accessed August 8, 2013.
Scleroderma. National Institute of Arthritis and Musculoskeletal and Skin Diseases website. Available at: http://www.niams.nih.gov/Health%5FInfo/Scleroderma/default.asp . Updated August 2012. Accessed August 8, 2013.
What is scleroderma? Scleroderma Foundation website. Available at: http://www.scleroderma.org/site/PageServer?pagename=patients%5Fwhatis . Accessed August 8, 2013.
- Reviewer: Rosalyn Carson-DeWitt, MD; Brian Randall, MD
- Review Date: 08/2013
- Update Date: 05/11/2013