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(Chorioretinitis; Choroiditis; Retinitis; Retinal Vasculitis; Vitritis)
Posterior uveitis is inflammation of the back segment of the uvea. The uvea is the middle layer of the eye. Posterior uveitis affects the retina and choroid, which are layers found in the back of the eye. The retina has the rods and cones that allow you to see.
Posterior uveitis is a potentially serious condition. Posterior uveitis requires care from your doctor to prevent vision loss.
|Anatomy of the Eye|
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Posterior uveitis may be caused by infection or by autoimmune disorders. It may also appear as a result of an infection in the past.
Factors that may increase your chance of posterior uveitis include:
- Autoimmune disorders, such as:
- Infections, such as:
- Weak immune status
- Exposure to pets, raw or undercooked meat, or contaminated water
- HLA-A29 gene
Posterior uveitis may cause:
- Redness in the eye
- Blurred or loss of vision
- Seeing floating objects in your vision
- Sensitivity to light or glare
- Excessive tearing
- Sensation of sparks or flashes of light
- Impaired night vision
- Impaired color vision
- Distortion of objects
Your doctor will ask about your symptoms and medical history. A physical exam will be done.
To prepare for a complete eye exam, drops may be put in your eyes to numb them and to dilate your pupils. The slit lamp, a special microscope to examine the eye, will focus a high-powered beam of light into your eye to examine the cornea and other eye structures. The doctor may measure the pressure in your eyes.
Your bodily fluids may be tested to determine a possible cause. This can be done with blood tests.
Most often treatment will focus on relieving the symptoms of posterior uveitis until it goes away. It is important to follow treatment recommendations to prevent complications or recurrence.
Focus may be on treating the underlying cause.
Posterior uveitis may be treated with:
- Oral or corticosteroid injections to control inflammation
- Medications to treat infection (if present)
- Medications that suppress the effects of the immune system
- Biological response modifiers to change immune response
National Eye Institute (NEI)
Canadian Ophthalmological Society
Canadian Association of Optometrists
Bou G, Figueroa MS, et al. Value of PCR for detection of Toxoplasma gondii in aqueous humor and blood samples from immunocompetent patients with ocular toxoplasmosis. J Clin Microbiol. 1999;37(11):3465-3468.
Facts about uveitis. National Eye Institute (NEI) website. Available at: https://nei.nih.gov/health/uveitis/uveitis. Updated August 2011. Accessed November 4, 2015.
Lanzafame M, Trevenzoli M, et al. Clinical picture: Tuberculous chorioretinitis. Lancet. 2001;357(9266):1390.
Posterior uveitis. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T326288/Posterior-uveitis. Updated September 18, 2016. Accessed September 26, 2016.
Yang MB. Patient complains of blurry vision in right eye for 2 weeks. Ophthalmology Times. 1997;22(12):18-20.
1/28/2011 DynaMed Plus Systematic Literature Surveillance http://www.dynamed.com/topics/dmp~AN~T326288/Posterior-uveitis: Berrébi A, Assouline C, Bessieres MH, et al. Long-term outcome of children with congenital toxoplasmosis. Am J Obstet Gynecol. 2010;203(6):552.e1-e6.
- Reviewer: Michael Woods, MD
- Review Date: 11/2015
- Update Date: 06/11/2015